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Milton Keynes Formulary
Milton Keynes University Hospital NHS Foundation Trust
Milton Keynes Clinical Commissioning Group
Milton Keynes Community Health Services
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 Formulary Chapter 4: Central nervous system - Full Chapter
04.07.04.01  Expand sub section  Treatment of the acute migraine attack
04.07.04.01  Expand sub section  Analgesics
04.07.04.01  Expand sub section  5HT1 agonists
Sumatriptan
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First Choice
Green

(1st line choice triptan)

  • Tablets 50mg, 100mg
  • Injection 6mg/0.5mL syringe

Notes:

In general, a triple drug combination taken together works best for the acute treatment of migraine:

  • a 5HT1 receptor agonists (known as a 'Triptan'), e.g. Sumatriptan
  • a Non-Steroidal Anti-inflammatory Drug (NSAID), e.g. Ibuprofen or Naproxen or Aspirin (this should be avoided in children under 16 years of age) or Paracetamol
  • an Anti-emetic, e.g. Metoclopramide, Prochlorperazine or Domperidone
 
Zolmitriptan
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Formulary
Green
  • Tablets 2.5mg
  • Orodispersible tablets 2.5mg

 

Notes:

In general, a triple drug combination taken together works best for the acute treatment of migraine:

  • a 5HT1 Receptor agonists (known as a ‘Triptan’), e.g. Sumatriptan or Zolmitriptan
  • a Non-Steriodal Anti-inflammatory Drug (NSAID), e.g. Ibuprofen or Naproxen or Aspirin (this should be avoided in children under 16 years of age) or Paracetamol
  • an Anti-emetic, e.g. Metoclopramide, Prochlorperazine or Domperidone
 
   
04.07.04.01  Expand sub section  Ergot alkaloids
04.07.04.01  Expand sub section  Anti-emetics to top
04.07.04.01  Expand sub section  Other drugs for migrane
 ....
 Non Formulary Items
Almotriptan  (Almogran®)

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Non Formulary
 
Eletriptan  (Relpax)

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Non Formulary
 
Frovatriptan

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Non Formulary
 
Naratriptan

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Non Formulary
 
Rizatriptan

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Non Formulary
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
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Link to adult BNF
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Link to children's BNF
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Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Green

Routine prescribing within licensed indication  

Amber 1

Specialist recommendation followed by GP initiation and continuation  

Amber 2

Specialist or GP initiation in line with local guideline after 1st line failure followed by GP continuation   

Amber 3

Specialist initiation and stabilisation followed by GP continuation  

Amber SCG

Specialist initiation and stabilisation followed by GP continuation in line with an agreed shared care guideline  

Red

Hospital or specialist prescribing only  

Red Red

These medicines have been evaluated and rejected by MKPAG and are NOT approved for use within MK. They are not recommended for use because of lack of clinical effectiveness, cost effectiveness or safety.  

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