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Milton Keynes University Hospital NHS Foundation Trust
Milton Keynes Clinical Commissioning Group
Milton Keynes Community Health Services
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 Formulary Chapter 4: Central nervous system - Full Chapter
04.03.01  Expand sub section  Tricyclic and related antidepressant drugs
04.03.01  Expand sub section  Tricyclic antidepressants
Amitriptyline
(Antidepressant)
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Formulary
Green
  • Tablets 10mg, 25mg, 50mg
  • Oral solution 25mg in 5mL and 50mg in 5mL
 
   
Clomipramine
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Formulary
Green

Capsules 10mg, 25mg, 50mg

 
   
Dosulepin
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Formulary
Amber 2

Note: Classed as a "Low Value Medicine"

  • Capsules 25mg
  • Tablets 75mg

 Dosulepin Commissioning Statement:

  • Prescribers should not initiate Dosulepin for any new patient.
  • Dosulepin should be discontinued from primary care prescribing (deprescribed), with support from specialist services if necessary.
  • If, in exceptional circumstances, (where the prescribing clinician considers no other medicine or intervention is clinically appropriate and available for the individual) there is a clinical need for dosulepin to be prescribed in primary care, this should be undertaken in a cooperation agreement with a multi-disciplinary team and/or other healthcare professional.
  • Patient Information Leaflet can be found on the formulary website at: 

Changes to dosulepin prescribing

 
   
Imipramine
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Formulary
Green

Tablets 10mg, 25mg

 
   
Lofepramine
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Formulary
Green

Tablets 70mg

 
   
04.03.01  Expand sub section  Related antidepressants
 ....
 Non Formulary Items
Amitriptyline and perphenazine  (Triptafen)

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Non Formulary
 
Amitriptyline and perphenazine  (Triptafen-M)

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Non Formulary
 
Doxepin

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Non Formulary
 
Nortriptyline

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Non Formulary
 
Trimipramine

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Non Formulary
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
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Link to adult BNF
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Link to children's BNF
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Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Green

Routine prescribing within licensed indication  

Amber 1

Specialist recommendation followed by GP initiation and continuation  

Amber 2

Specialist or GP initiation in line with local guideline after 1st line failure followed by GP continuation   

Amber 3

Specialist initiation and stabilisation followed by GP continuation  

Amber SCG

Specialist initiation and stabilisation followed by GP continuation in line with an agreed shared care guideline  

Red

Hospital or specialist prescribing only  

Red Red

These medicines have been evaluated and rejected by MKPAG and are NOT approved for use within MK. They are not recommended for use because of lack of clinical effectiveness, cost effectiveness or safety.  

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