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Milton Keynes Formulary
Milton Keynes University Hospital NHS Foundation Trust
Bedfordshire, Luton and Milton Keynes Clinical Commissioning Group
Milton Keynes Community Health Services
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 Formulary Chapter 18: Emergency Treatment of Poisoning - Full Chapter
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18  Expand sub section  Poisoning
Andexanet alfaBlack Triangle (Ondexxya®)
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Formulary
Red
High Cost Medicine

200 mg powder for solution for infusion vials

For reversing anticoagulation from apixaban or rivaroxaban in adults with life-threatening or uncontrolled bleeding only if the bleed is in the gastrointestinal tract.

To be used in accordance with the NICE TA (see link below).

Refer to Haematology for advice.

 
Link  NICE TA697: Andexanet alfa for reversing anticoagulation from apixaban or rivaroxaban
   
Digoxin specific antibody fragments (Digifab®)
(Antidote)
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Formulary
Red
High Cost Medicine

Digoxin Immune Fab - Injection, DigiFab® 40mg per vial (Hospital use only)

Notes:

  • For reversal of life-threatening digoxin overdose
  • Available on a named-patient basis only
  • Manufacturer has no out-of-hours service
 
   
Glyceryl Trinitrate
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Formulary
Green
  • Tablets, sublingual 300 micgrograms, 500 micrograms, 600 micrograms
  • Spray 400 micrograms
  • Patches 5mg/24 hours, 10mg/24hours
  • Ointment 2%
  • Buccal modified release tablets 2mg, 3mg, 5mg (Hospital only)
  • Injection 5mg in 5ml,50mg in 10ml, 25mg in 5mL (Hospital only)
 
   
18  Expand sub section  Body Temperature
18  Expand sub section  Nerve agents
18  Expand sub section  Pesticides
18  Expand sub section  Snake bites and animal stings to top
18  Expand sub section  Convulsion
18  Expand sub section  Removal and Elimination
18  Expand sub section  Removal from the Gastro-intestinal tract
18  Expand sub section  Prevention of absorption
18  Expand sub section  Active elimination techniques to top
18  Expand sub section  Specific Drugs
18  Expand sub section  Alcohol
18  Expand sub section  Analgesics (non-opioid)
18  Expand sub section  Analgesics (opioid)
18  Expand sub section  Antidepressants to top
18  Expand sub section  Antimalarials
18  Expand sub section  Beta Blockers
18  Expand sub section  Calcium-channel blockers
18  Expand sub section  Hypnotics and anxiolytics
18  Expand sub section  Iron Salts to top
18  Expand sub section  Lithium
18  Expand sub section  Phenothiazines and related drugs
18  Expand sub section  Stimulants
18  Expand sub section  Theophylline
18  Expand sub section  Other poisons to top
18  Expand sub section  Cyanides
18  Expand sub section  Ethylene glycol and methanol
18  Expand sub section  Heavy Metals
18  Expand sub section  Noxious gases
18  Expand sub section  CS Spray to top
 ....
 Non Formulary Items
Acetylcysteine  (Parvolex)
(Paracetamol overdose)

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Non Formulary
Link  MHRA information page about the changes in Sept 2012
Link  Treating paracetamol overdose with intravenous acetylcysteine: new guidance
 
Activated charcoal
(antidote)

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Non Formulary
 
Antivenoms for non-indigenous venomous animals

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Non Formulary
Link  Toxbase: National Poisons Information Service
 
Atropine
(Antidote)

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Non Formulary
 
Benzatropine
(antidote)

Non Formulary
Link  Toxbase: National Poisons Information Service
 
Botulism antitoxin  (antidote)

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Non Formulary
 
Calcium chloride
(antidote)

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Non Formulary
 
Calcium gluconate
(Poisoning)

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Non Formulary
 
Calcium gluconate gel
(antidote)

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Non Formulary
 
Cyproheptadine  (Periactin®)

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Non Formulary
 
Dantrolene
(Poisoning)

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Non Formulary
 
Desferrioxamine
(Poisoning)

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Non Formulary
 
Diazepam
(antidote)

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Non Formulary
 
Dicobalt edetate
(cyanide poisoning)

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Non Formulary
 
Dimercaprol
(antidote)

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Non Formulary
Link  Toxbase: National Poisons Information Service
 
DMPS (unithiol)
(antidote)

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Non Formulary
Link  Toxbase: National Poisons Information Service
 
DMSA (succimer)
(antidote)

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Non Formulary
Link  Toxbase: National Poisons Information Service
 
Ethanol (alcohol) injection
(antidote)

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Non Formulary
 
European Viper Venom Antivenom
(antiserum / antidote)

Non Formulary
 
Flumazenil
(antidote)

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Non Formulary
 
Folinic acid
(Poisoning)

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Non Formulary
 
Fomepizole

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Non Formulary
High Cost Medicine
 
Glucagon  (GlucaGen® Hypokit)
(Poisoning)

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Non Formulary
 
Glucarpidase  (Carboxypeptidase)
(Poisoning)

Non Formulary
High Cost Medicine
 
Hydroxocobalamin  (Cyanokit®)
(antidote)

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Non Formulary
 
Lorazepam
(antidote)

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Non Formulary
 
Macrogol '3350'  (Klean-Prep®)
(Poisoning)

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Non Formulary
 
Mesna
(antidote)

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Non Formulary
 
Methionine
(paracetamol overdose)

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Non Formulary
 
Methylthioninium chloride  (Proveblue®)
(for IV use)

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Non Formulary
Link  MHRA safety update April 2009
 
Naloxone
(antidote)

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Non Formulary
 
Octreotide
(antidote)

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Non Formulary
 
Penicillamine  (Distamine)
(antidote)

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Non Formulary
 
Phentolamine
(antidote)

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Non Formulary
 
Phytomenadione  (Vitamin K1)
(antidote)

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Non Formulary
 
Potassium ferric hexacyanoferrate  (Berlin / Prussian Blue)
(antidote)

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Non Formulary
Link  Toxbase: National Poisons Information Service
 
Pralidoxime chloride

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Non Formulary
 
Pralidoxime chloride  (Protopam®)
(antidote)

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Non Formulary
 
Procyclidine
(Poisoning)

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Non Formulary
 
Protamine Sulphate
(Heparin overdose / reversal)

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Non Formulary
 
Pyridoxine
(antidote)

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Non Formulary
 
Sodium bicarbonate
(Poisoning)

Non Formulary
 
Sodium calcium edetate
(antidote)

Non Formulary
 
Sodium nitrite
(antidote)

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Non Formulary
 
Sodium thiosulfate
(antidote)

Non Formulary
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Green

Routine prescribing within licensed indication  

Amber 1

Specialist recommendation followed by GP initiation and continuation  

Amber 2

Specialist or GP initiation in line with local guideline after 1st line failure followed by GP continuation   

Amber 3

Specialist initiation and stabilisation followed by GP continuation  

Amber SCG

Specialist initiation and stabilisation followed by GP continuation in line with an agreed shared care guideline  

Red

Hospital or specialist prescribing only  

Red Red

These medicines have been evaluated and rejected by MKPAG and are NOT approved for use within MK. They are not recommended for use because of lack of clinical effectiveness, cost effectiveness or safety.  

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