Milton Keynes Formulary
Milton Keynes University Hospital NHS Foundation Trust
Milton Keynes Clinical Commissioning Group
Milton Keynes Community Health Services

 
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7 Obstetrics, Gynaecology, and urinary-tract disorders
07-01-01 Prostaglandins and oxytocics

Carboprost Hemabate®
Formulary

Injection 250 micrograms /1ml

 

Carboprost is only indicated for postpartum haemorrhage due to uterine atony
in patients unresponsive to ergometrine and oxytocin.

Misoprostol (unlicensed) can be used in postpartum haemorrhage when oxytocin, ergometrine, and carboprost are not available or are in apporpriate.

Tranexamic acid is used to decrease blood loss in surgery and health conditions associated with increased bleeding. there have been some reviews that have found that tranexamic acid is also effective in reducing blood loss post partum.


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Dinoprostone Prostin E2®
Formulary

Prostin E2® Pessary Vaginal tablets 3mg
Propess® Vaginal delivery system 10mg
Prostin E2® IV injection 10mg/ml, 1mg/ml

use as per NICE clinical guideline 70 "induction of Labour" (July 2008)


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Ergometrine Maleate
Formulary

Injection 500micrograms in mL


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Ergometrine Maleate and Oxytocin Syntometrine®
Formulary

Injection containing ergometrine maleate 500micrograms and oxytocin 5 units in 1 mL


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Gemeprost
Formulary

Pessary 1mg


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Misoprostol
Formulary

Tablets 200 micrograms

Link  DTB review on use for postpartum haemorrhage, 2010
 

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Oxytocin Syntocinon®
Formulary

Injection 5 units in 1mL, 10 units in 1mL


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Carbetocin Pabel®
Non Formulary

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Misoprostol vaginal delivery system Mysodelle®
Non Formulary
Link  MHRA: reports of excessive uterine contractions (tachysystole)
 

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