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Milton Keynes Formulary
Milton Keynes University Hospital NHS Foundation Trust
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 Formulary Chapter 9: Nutrition and blood - Full Chapter
09.01.04  Expand sub section  Drugs used in autoimmune thrombocytopenic purpura
Anagrelide
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Formulary
Red

Capsules 500 micrograms 

 
   
Eltrombopag (Revolade)
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Formulary
Red
High Cost Medicine

Tablets 25mg, 50mg

Advice for healthcare professionals:


• Eltrombopag is highly coloured (reddish-brown) and can cause serum discolouration and interference with the test results of creatinine and bilirubin.


• Be aware that interference with bilirubin (falsely low/normal results) and creatinine (falsely high/normal results) may occur in patients taking eltrombopag.


• If bilirubin and/or creatinine laboratory results are inconsistent with clinical observations, request re-testing using another method to determine the validity of the result.


• The laboratory may consider susceptibility to serum discolouration and other factors that may be relevant when selecting an alternative test method.


• Report suspected adverse drug reactions, including any harm that
occurs from a medicine interfering with laboratory test results, to the Yellow Card Scheme.

 
Link  MHRA: eltrombopag interference with creatinine and bilirubin tests
Link  NICE TAG 293: Eltrombopag for treating chronic ITP
   
Lusutrombopag
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Formulary
Red
High Cost Medicine

3mg tablets

 
Link  NICE TA617: Lusutrombopag for treating thrombocytopenia in people with chronic liver disease needing a planned invasive procedure
   
Romiplostim (Nplate)
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Red
High Cost Medicine

Injection, powder for reconstitution 250 microgram vial 

 
Link  NICE TA221: Thrombocytopenic purpura - romiplostim
   
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Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
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Link to adult BNF
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Link to children's BNF
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Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Green

Routine prescribing within licensed indication  

Amber 1

Specialist recommendation followed by GP initiation and continuation  

Amber 2

Specialist or GP initiation in line with local guideline after 1st line failure followed by GP continuation   

Amber 3

Specialist initiation and stabilisation followed by GP continuation  

Amber SCG

Specialist initiation and stabilisation followed by GP continuation in line with an agreed shared care guideline  

Red

Hospital or specialist prescribing only  

Red Red

These medicines have been evaluated and rejected by MKPAG and are NOT approved for use within MK. They are not recommended for use because of lack of clinical effectiveness, cost effectiveness or safety.  

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